Figure 4.

Influence of LPS on the increase in basal DBP induced by ES (1 Hz, 1 ms, 50 V for 10 s) of the preganglionic sympathetic nerve fibers or by injection of NA (1–3 nmol kg⁻¹) in pithed and vagotomized rats pretreated with pancuronium (0.8 μmol kg⁻¹). For the experimental protocol, see Figure 1. The ratios S₂/S₁, S₃/S₁ and S₄/S₁ for the increase in DBP in LPS-treated animals were expressed as percentages of the corresponding ratios obtained in vehicle-treated animals (% of control). Means±s.e.m. of 4–9 rats. ^*P<0.05, ^***P<0.001 compared to the corresponding control.