Table 2.
n | Control | 1 | 3 | 10 | |
---|---|---|---|---|---|
rNav1.2 | 7 | 0.62±0.06 | 0.52±0.05* | ||
3 | 0.61±0.08 | 0.53±0.10* | |||
3 | 0.41±0.02 | 0.35±0.02* | |||
rNav1.4 | 6 | 0.56±0.04 | 0.55±0.04 | ||
3 | 0.39±0.04 | 0.33±0.04** | |||
3 | 0.49±0.07 | 0.41±0.07 | |||
rNav1.5 | 6 | 0.71±0.09 | 0.71±0.07 | ||
3 | 0.46±0.02 | 0.39±0.01* | |||
3 | 0.51±0.05 | 0.45±0.03 |
Time-to-peak INa (ms) is given for the control (no CTX) and the indicated concentrations of CTX (μmol l−1). CTX accelerated time-to-peak INa most markedly in isoform rNav 1.2, that is, by 0.1 ms.
P<0.05 vs control,
P<0.01 vs control.