Figure 3.

Effects of 18β-glycyrrhetinic acid on membrane potential, cell input resistance (rapid deflections) and tension. (a) Original recordings of simultaneous measurements of membrane potential and isometric tension of isolated mesenteric small arteries activated with noradrenaline (NA). (b) Bars illustrate the reversibility of 18β-glycyrrhetinic acid responses on membrane potential and tension: arteries (n=7) were stimulated with NA, superfused with 18β-glycyrrhetinic acid, rinsed for 15 min and stimulated with NA again. No significant difference between first and second NA stimulation was found. (c) Effects of 18β-glycyrrhetinic acid on membrane potential and cell input resistance in isolated mesenteric small arteries under resting conditions. 18β-glycyrrhetinic acid was present as indicated.