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Original recordings of the effects of heptanol (a), 18αGA (b) and 18βGA (c) on tension and [Ca2+]i in arteries stimulated with a submaximal concentration of noradrenaline (NA). (d) Addition of 150 μM heptanol relaxes the artery and inhibits NA-induced oscillations, but force can be recovered by increasing the NA concentration; oscillation reappeared, but with reduced amplitude. (e) In the presence of 30 μM 18βGA NA evokes only tonic contraction.
