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Kinetics of IL-3-induced mediator generation from basophils. Basophils were challenged with IL-3 (100 ng ml−1) for time periods up to 24 h and the generation of (a) IL-13 and (b) histamine were monitored. Values are means±s.e.m., n=4. IL-4 generation was also monitored in these experiments but only one donor generated IL-4 to an appreciable degree.
