Table 2.

Parameters of renal function

Age (weeks)	Placebo	Placebo+Ica	AVE	AVE+Ica
Creatinine clearance (ml kg−1 min−1)
21 (baseline)	6.8±0.4
31	10.0±0.3	9.2±0.3	8.4±0.3*	8.7±0.4*
39	ND	ND	ND	ND
Urinary albumin–creatinine ratio (mg mmol−1)
21 (baseline)	1331±230
31	957±102	1193±176	135±12*	211±60*
39	1257±206	1732±225	101±17*	172±41*

^*P<0.0125 vs Placebo; ND, not determined.