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. 2004 Aug 16;143(2):257–268. doi: 10.1038/sj.bjp.0705927

Figure 3.

Figure 3

Percentage of reactive oxygen species (ROS) production in bronchoalveolar lavages (containing 98% macrophages) of LPS-treated rats at the activation peak induced by 2 μM fMLP in the presence of PDE4 inhibitors or MAPK inhibitors (C+=positive control, W=0.05 nM wortmannin). Statistical analysis: the effects of each compound were compared to a theoretical mean of 100% representing the positive control, using the Holm's multiple test procedure (*P<0.01, **P<0.001, ***P<0.0001).