Effect of RU486 on the upregulation of bone-marrow eosinopoiesis by surgery. Data are means±s.e.m. of the percent eosinophils present in (a) bone-marrow and (b) 7-day bone-marrow liquid cultures. NAÏVE, naïve controls, SHAM+Vehicle, vehicle-treated, sham-implanted mice, SHAM+RU486, RU486-treated, sham-implanted mice. Bone-marrow counts and culture were established 24 h after surgery. Multiple comparisons were carried out and P-values are indicated for all significant differences. Numbers of experiments for the three groups were, respectively, 17, 36, and 10 in panel a; and 14, 31, and 9 in panel b.