Figure 4.

Effect of adrenal gland blockade and removal on the response of bone-marrow to subsequent surgery. Data are means±s.e.m. of the percent eosinophils present at day 0 in bone-marrow cytocentrifuge smears. NAÏVE, naïve controls, Vehicle, vehicle-treated mice, Metyr, metyrapone-treated mice. Mice were submitted or not to surgical removal of the adrenal glands (ADX) and further submitted or not to sham implantation surgery (SHAM), 15 days after ADX. Bone-marrow counts were made 24 h after the sham implantation surgical procedure. Multiple comparisons were carried out and P-values are indicated for all significant differences. Numbers of experiments for the six groups were, respectively, 5, 5, 5, 4, 5, and 3.