Ineffectiveness of adrenergic blockade in preventing the upregulation of bone-marrow eosinophilia by surgery. Data are means±s.e.m. of the percent eosinophils present in bone-marrow. NAÏVE, naïve mice, SHAM+Vehicle, vehicle-treated, sham-implanted mice, SHAM+Adrenergic blockers, sham-implanted mice pretreated with prazosin (PRAZ), propranolol (PROP), prazosin and propranolol (PROP+PRAZ) or yohimbine (YOH). Bone-marrow counts were made 24 h after surgery. Multiple comparisons were carried out. P-value is shown for the difference between vehicle-treated, sham-implanted mice and naïve controls. All differences among sham-implanted (vehicle-treated and drug-treated) mice were nonsignificant (NS). Numbers of experiments for the six groups were, respectively, 5, 4, 5, 4, 3, and 3.