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Effects of carcinine on locomotor activity in mice as evaluated by the open-field test. Carcinine or thioperamide was intraperitoneally administrated 60 min before the test. Distances of ambulation were accumulated every 9 min. Each value was expressed as the mean±s.d. of 13 to 15 mice. *P<0.05, statistical significance of difference between saline- and carcinine- or thioperamide-treated groups.
