Table 1.
Receptor | S1P1 | S1P2 | S1P3 | S1P4 | S1P5 | |||||
---|---|---|---|---|---|---|---|---|---|---|
mRNA | Protein | mRNA | Protein | mRNA | Protein | mRNA | Protein | mRNA | Protein | |
Ventricular cardiomyocytes | +++a, ++b | +++a | +a, ++b | +a | ++ab | ++a | −b | ++b | ||
Septal cardiomyocytes | +++a | +++a | +a | +a | ++a | ++a | −b | ++b | ||
Atrial cardiomyocytes | +++a, ++b,c | +++a | +a, ++b,c | +a | ++a,b,c | ++a | −b | ++b | ||
Coronary artery endothelial cells | +++a | +++a | −a | −a | ||||||
Coronary artery smooth muscle cells | −a | −a, +d | −a | −a | ++a | ++a | ||||
Aortic endothelial cells | −a, +++e,f | −a,e, +f | −a, +++e | |||||||
Aortic smooth muscle cells | −a,g, +h,i,k,l | −a, +d | +a, +++g,h,i | +a, ++d | +++a,h,i, ++g | +++a, ++d | −g,j | −g,j | ||
Umbilical vein endothelial cells | +++f,g | −g, +f | ++f | −g | −g | |||||
+++: high expression; ++: intermediate expression; +: low expression; −: not detected.