Table 2.
The effect of [Dmt1]DALDA chronic treatment on gene expression in brain
| Gene | Saline control | 3-Day treatment | 7-Day treatment | P |
|---|---|---|---|---|
| MOR | 7.42±0.20 | 6.19±0.34 | 6.05±0.17 | <0.01 |
| DOR | 5.68±0.08 | 5.09±0.24 | 5.04±0.21 | <0.01 |
| KOR | 6.71±0.15 | 6.54±0.37 | 6.04±0.26 | 0.15 |
| PPE | 1.01±0.21 | 1.00±0.20 | 0.02±0.09 | <0.05 |
| PPD | 6.12±0.20 | 5.69±0.21 | 5.43±0.28 | <0.05 |
| POMC | 8.04±0.30 | 8.43±0.25 | 7.92±0.06 | 0.41 |
Data are given as mean±s.e.m. of ΔCT values, n=5. P-value, compared with treatments over time and saline control, was determined by one-way ANOVA analysis.