Table 1.

Effects of different pharmacological agents on the acute effect of 1 nM 17β-estradiol in porcine coronary arteries

Treatment	Maximum contraction (% KCl)
Control	138±1.9
17β-estradiol 1 nM	119±1.4	*
Isoproterenol 1 nM	124±2.7	*
17β-estradiol 1 nM+isoproterenol 1 nM	123±2.9	*
Control	145±3.6
17β-estradiol 1 nM	124±4.8	*
8-Br-cAMP 10 μM	125±5.1	*
17β-estradiol 1 nM+8-Br-cAMP 10 μM	123±4.8	*
Control	141±4.0
17β-estradiol 1 nM	122±7.1	*
8-Br-cGMP 3 μM	122±4.1	*
17β-estradiol 1 nM+8-Br-cGMP 3 μM	126±5.1

Data represent mean±s.e.m. n=6–7 in each treatment group.

^*P<0.05 vs corresponding controls (ANOVA–Dunnett's).