Table 4.

ATP-induced increase in [Ca²⁺]_i in cardiomyocytes at different times after the induction of MI in animals with or without imidapril

	Untreated animals		Treated animals
	Basal [Ca2+]i (nM)	ATP-induced increase in [Ca2+]i (% of basal)	Basal [Ca2+]i (nM)	ATP-induced increase in [Ca2+]i (% of basal)
Sham	113±5.4	35±1.7	119±6.6	32±0.8
2 weeks	119±4.7	34±1.5	116±3.9	30±1.7
4 weeks	116±7.5	26±1.4*	121±4.1	33±1.5†
8 weeks	121±4.9	11±0.8*	119±3.9	26±2.3†
16 weeks	116±5.2	6±1.2*	120±5.2	24±3.4†

Values are mean±s.e.m. of six animals in each group. [Ca²⁺]_i was measured 100 s after the addition of ATP (50 μM).

^*P<0.05 vs sham control values;

^†P<0.05 vs corresponding values for the untreated group.