Effect of chronic treatment with the ACEI, captopril (100 mg kg−1 day−1, SHR-CAP), on the stress–strain relationships in young (6 months, left) and old (15 months, right) SHR compared to age-matched normotensive WKY. Values are means±s.e.m. ID, internal diameter of cerebral arterioles for mean cerebral arteriolar pressure steps of 5 mmHg (35–39 to 5–9 mmHg); IDo, ID at the lowest pressure step.