Table 1.
Baseline values for cerebral arterioles after deactivation (EDTA) in WKY and SHR of different ages treated or not with captopril
| Parameters | WKY | SHR | WKY | SHR | SHR | SHR |
|---|---|---|---|---|---|---|
| Age (months) | 6 | 6 | 15 | 15 | 6 | 15 |
| Captopril (mg kg−1 day−1) | No | No | No | No | 105±2 | 94±1 |
| N | 10 | 10 | 15 | 8 | 13 | 11 |
| Baseline ID (μm) | 65±4 | 40±1* | 59±3 | 40±2* | 51±2† | 51±3† |
| EIR Index | NA | 98 | NA | 94 | 95 | 92 |
| HIR Index | NA | 2 | NA | 4 | 4 | 10 |
Eutrophic inward remodeling (EIR) and hypertrophic inward remodeling (HIR) indices were calculated as described previously (Baumbach & Heistad, 1989).
*
P⩽0.05 versus age-matched WKY.
†
P⩽0.05 versus age-matched SHR.