Figure 3.
EtOH depression and withdrawal hyper-responsiveness are calcium dependent. (a) Individual traces from a motor neuron showing no withdrawal hyper-responsiveness when the recording pipette contains 30 mM BAPTA instead of 11 mM EGTA. (b) Time course of the mean effects of ethanol (n=8) on the area of NMDA-evoked currents. (c) Histogram showing less ethanol depression and no withdrawal hyper-responsiveness. Ethanol and wash were measured at 18 min after 100 mM ethanol application and washout, respectively. One-way ANOVA test, *P<0.05 compared to control.