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. 2005 Jan 10;144(3):405–415. doi: 10.1038/sj.bjp.0706088

Figure 2.

Figure 2

Typical isometric force recording generated in rings of piglet saphenous vein treated as described in Methods. Substances were added to the bathing solution at the points indicated. Addition of PGE2 resulted in rapid tissue relaxation responses which were stably maintained. Inset: Mean PGE2 concentration–effect curve in rings of PE (1 μM) precontracted PSV. A four-parameter logistic equation was fitted to individual curve data as described in Methods to generate curve parameters as follows: pEC50=8.6±0.2, nH=1.9 (1.5–2.4), α=98±3%. Data are mean±s.d.; data for slope are geometric mean with 95% confidence intervals; n=6.