Table 2.
Potencies of bimatoprost and prostanoid FP receptor agonists on human myometrial strips taken from nonpregnant and pregnant donors
Compound | Nonpregnant Myometrium ED1 (nmol) | Pregnant myometrium ED1 (nmol) |
---|---|---|
Bimatoprost | >100 | >500 |
17-phenyl PGF2α | 0.06 | 6.0 |
Fluprostenol | 0.04a | 0.61b |
PGF2α | 0.04a | 0.5b |
Mean ED1 value±s.e.m. (nmol) at a T/B ratio equal to 1.