Figure 6.

In vivo anti-inflammatory efficacy of lumiracoxib and diclofenac. Inflammation, hyperalgesia and pyresis were induced as described in the Methods section. Percent inhibition of (a) carrageenan-induced paw oedema measured 4 h after dosing (mean from two experiments, n=6 rats per treatment group in each experiment), (b) hyperalgesia 1 h after dosing (mean from three experiments, n=6 rats per treatment group in each experiment) and (c) pyresis 2 h after dosing (mean from four experiments, n=3 rats per treatment group in each experiment). The values shown are mean percent inhibition (±s.e.m.) for lumiracoxib and diclofenac.