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Effects of N/OFQ and NOP-SA (selective agonist of NOP receptor: [Arg14,Lys15]N/OFQ) on SP-induced microvascular leakage of anestethized rabbits pretreated with atropine (1 mg kg−1), propranolol (1 mg kg−1) and phosphoramidon (1 mg kg−1). SP (0.3 μg kg−1, i.v.) was injected 5 min before dye infusion. Data are expressed as mean±s.e.m., n=5 per group. #P<0.01 vs saline.
