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(a) Potassium chloride (120 mM)-induced contraction of SMA (n=6–8) from db/+ and db/db mice under low and high oxygen tension. (b) Concentration–response curves to PE of SMA from db/+ and db/db mice (n=7–8) under low and high oxygen tension. *P<0.01 compared to db/+ mice under low oxygen tension and Ψ, P<0.01 compared to db/+ mice under high oxygen tension.
