Figure 6.
Effect of Iso on enzymatic activity of PKA in ventricular myocytes from control, Ovx, and Ovx+E rats. (a) Iso-stimulated PKA activity, (b) Iso-stimulated PKA activity in the presence of bisoprolol (1 μM), and (c) Iso-stimulated PKA activity. The Iso-stimulated PKA activity is defined as the difference in PKA activity with/without Iso preincubation in the absence/presence of bisoprolol, respectively. Values are expressed as mean±s.e.m. of triplicate measurements from three hearts in each group. *P<0.05 vs corresponding values without Iso. #P<0.05 vs corresponding values with Iso.