Figure 4.

Effects of P2 receptor antagonists on dilation responses of glomeruli to Ap₄A and Ap₅A. Glomeruli were incubated with buffer (open columns), 10 μM suramin (rising right columns) or 50 μM reactive blue 2 (RB-2, solid columns) for 2 min and then with ATP, Ap₄A and Ap₅A (each at 1 μM) for 5 min. Results are expressed as the percentage of changes of basal value±s.e.m. for n=3–4 experiments. ^*P<0.05 agent+antagonist vs agent+buffer.