Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IC50 values obtained from MPEP- and MTEP-induced inhibition of basal values of transiently transfected hmGlu5a WT or mutated receptors by IP accumulation measurement
| MPEP (nM) | MTEP (nM) | |
|---|---|---|
| WT | 25.7±4.1 | 71.4±110 |
| C57S | 17.0±8.4 | 55.9±20 |
| C93S | 20.7±6.2 | 48.5±15 |
| C99S | 8.8±6.1 | 19.4±46 |
| C129S | 16.5±6.9 | 60.4±26 |
| C57/99S | 11.3±7.6 | ND |
| 4C-S | ND | ND |
Average±s.e.m. of n=3 independent experiments; ND, not determined.
