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Effect of downregulation of phorbol ester-sensitive PKC isoforms (PKC dr) on (a) short-term and (b) long-term inhibitory effects of IFN-γ (1000 U ml−1) on NHE activity. Columns represent means of seven experiments per group; vertical lines indicate s.e.m. values. *P<0.05, values significantly different from control values using the Student's t-test. The NHE activity in pH units s−1 was as follows: vehicle, 0.0030±0.0002; PKC dr, 0.0020±0.0002.
