Table 2.

Inhibitory effect of PDBu (100 nM) on NHE activity, effect of downregulation of phorbol ester-sensitive PKC isoforms (PKC dr, overnight treatment with 300 nM PDBu) on NHE activity after 0.5 h exposure to PDBu and effect of PD 98059 (10 μM), SB 203580 (10 μM), GW 5074 (150 nM) and EGCG (20 μM) on NHE activity after 0.5 h exposure to PDBu

	Vehicle	PDBu
Vehicle	100±6	45±3*
PKC dr	100±6	100±8
PD 98059	100±11	65±4*
SB 203580	100±5	67± 6*
GW 5074	100±11	63±4*
EGCG	100±9	59±6*

Values indicate means of 13 experiments per group.

^*P<0.05, values significantly different from control values using the Newman–Keuls test. The NHE activity in pH units s⁻¹ was as follows: vehicle, 0.0030±0.0002; PKC dr, 0.0020±0.0001; GW 5074, 0.0030±0.0003; PD 98059, 0.0025±0.0002; SB 203580, 0.0025±0.0003; EGCG, 0.0035±0.0003.