Figure 1.
Plasma concentrations of oxybutynin, DEOB and solifenacin over time after oral administration of oxybutynin (a) and solifenacin (b) in mice. Mice received oxybutynin (76.1 μmol kg−1) or solifenacin (62.4, 208 μmol kg−1) orally, and were then killed. Blood samples were taken from the descending aorta of each mouse. Each point represents the mean±s.e.m. of one to nine mice.