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Infarct size (left panel) and recovery of LVP (right panel) in hearts that were subjected to 45 min left anterior descending coronary artery occlusion, followed by 3 h of reperfusion, after either no pretreatment (C, control), preconditioning (PC, 15 min of occlusion followed by 10 min of reperfusion), or a 15-min exposure to vehicle (Veh), 100 nM aldosterone (Aldo), or 100 nM spironolactone (Spi). Values are mean±s.e.m. of six experiments. *P<0.05 vs control.
