Figure 6.
Effect of adenosine (25 μM) on normal and giant mepps in the presence of 4-AQA (30 μM). mepp amplitude histograms recorded in the presence of 30 μM 4-AQA before (a, control) and after application of 25 μM adenosine (b) are shown. Insets show the same data expressed as column graphs. As shown, adenosine selectively reduces the number of normal amplitude mepps without affecting those with amplitudes greater than twice the mode. The data shown were obtained from a single endplate; each recording period was 418.5 s in duration; Vm=−103 mV.