Figure 2.

Inhibition of membrane-bound [³H]AEA and cytosolic [³H]2-OG hydrolysis by AM404 and VDM11. Data are means±s.e.m. (when not enclosed by the symbols), n=3, of the activities expressed as % of controls treated with the same concentration of vehicle. The assays contained 0.125% fatty acid-free BSA (from Calbiochem). The substrate concentrations were 2 μM.