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Effects of PMA on myocardial infarct (a) and LDH release (b) in isolated perfused rat heart subjected to 30 min ischaemia and 120 min reperfusion. Experimental protocol is shown in the upper panel. PMA (0.1 μM) was administered for 10 min before 15 min of ischaemia. Che (5 μM) and 10 μM GF and 1 μM Pax were administered for 30 min before ischaemia. Data are expressed as individual values and mean±s.e.m.; n=10 in each group. **P<0.01 compared with the IR group.
