Table 1.

Biodistribution studies of [¹¹C]carvedilol in male Wistar rats 60 min post injection, expressed as DAR

	CsA dosage (mg kg−1)
Organ	0 (n=5)	5 (n=5)	10 (n=3)	15 (n=5)	25 (n=3)	50 (n=3)
Brain*	0.12 (0.06)	0.12 (0.09)	0.12 (0.07)	0.21 (0.19)	0.62 (0.19)	0.64 (0.38)
Heart	0.66 (0.13)	0.52 (0.19)	0.43 (0.16)	0.60 (0.33)	0.77 (0.22)	0.67 (0.45)
Lung	6.08 (2.58)	3.81 (1.47)	3.14 (1.91)	3.34 (1.69)	6.48 (1.81)	5.00 (3.83)
Liver	3.02 (1.58)	3.10 (2.34)	2.30 (1.39)	2.59 (1.73)	3.19 (1.49)	2.45 (1.87)
Kidney	1.33 (0.49)	1.01 (0.34)	0.81 (0.43)	1.02 (0.61)	2.34 (1.47)	1.92 (1.52)
Testis	0.28 (0.23)	0.30 (0.20)	0.24 (0.12)	0.18 (0.13)	0.30 (0.10)	0.37 (0.25)
Plasma	0.41 (0.31)	0.43 (0.30)	0.40 (0.36)	0.39 (0.33)	0.74 (0.48)	0.53 (0.19)

^*P=0.003.