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. 2005 Jun 6;145(8):1017–1026. doi: 10.1038/sj.bjp.0706289

Figure 3.

Figure 3

Effect of LNNA (100 μM) on the inhibitory responses obtained by EFS in NANC conditions at different stimulation frequencies (0.5 ms, 50 V cm−1 for 10 s). The magnitudes of the EFS-evoked responses are expressed as the % change in the amplitude (the amplitude of the inhibitory phase normalized to the amplitude of the muscle activity directly precedent to the inhibitory stimulus) and the values shown are mean±s.e. (a, b) LNNA abolishes the EFS-induced inhibitions at all frequencies in BALB/c and Cav1+/+, respectively. Significance is tested by ANOVA followed by Bonferroni's test (***P<0.001, n-value=7 for BALB/c and 6 for Cav1+/+). (c) LNNA significantly reduces the EFS-induced inhibitions only at 1 and 3 pps (*P<0.05, n-value=11), and had no effect on the inhibitions at 10 and 30 pps in Cav−/− mice.