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Effects of W-212393, 8-OH-DPAT, and melatonin on the circadian rhythm of body temperature in rats. Drugs were injected at CT6 (upper) or CT9 (lower). Data indicate the mean±s.e.m. of 5–8 rats. *P<0.05, **P<0.01, ***P<0.001 in comparison with vehicle by Dunnett's multiple comparison test.