Table B1.
W-212393 had no effect on enzyme activity (IC50>10 μM)
ATPase, H+/K+ (rabbit) |
Carbonic anhydrase (human) |
Catechol-O-methyltransferase (COMT) (porcine) |
Cyclooxygenase (COX-1) (human) |
HMG-CoA reductase (rat) |
Lipoxygenase (5-LO) (human) |
Monoamine oxidase (MAO-A) (human) |
Monoamine oxidase (MAO-B) (human) |
Nitric oxide synthase, inducible (iNOS) (mouse) |
Nitric oxide synthase, Neuronal (nNOS) (rat) |
Phosphodiesterase (PDE1) (bovine) |
Phosphodiesterase (PDE5) (human) |
Phospholipase (PLA2-I) (porcine) |
Phospholipase (PLC) (bacillus cereus) |
Protein serine/threonine kinase (Ca2+/calmodulin-dependent II) (rat) |
Protein serine/threonine phosphatase (calcineurin, PP2B) (human) |
Protein serine/threonine kinase (p38α) (human) |
Protein serine/threonine kinase (PKA), nonselective (bovine) |
Protein serine/threonine kinase (PKC), nonselective (rat) |
Protein tyrosine phosphatase (PTP1B) (human) |
Tyrosine hydroxylase (rat) |