Figure 8.

Effect of smooth muscle cell activation on the myogenic response. (a) Diameter changes in response to a pressure step from 10 to 40 mmHg in the control (ctrl), during EFS (EFS), in the presence of noradrenaline (NA), and during selective α₁- and α₂-receptor stimulation; a significantly different effect was observed during EFS, NA application, and selective α₁- and α₂-receptor stimulation compared to control (all P<0.01). (b) Diameter changes in response to the pressure steps indicated below the bars in the control (ctrl), in the presence of serotonin (Ser) and vasopressin (Vaso); at the step from 10 to 40 mmHg, a significantly different effect was observed during Ser and Vaso compared to control (both P<0.05); at the other pressure steps, no differences were found (P=0.53 and P=0.65).