Table 1.
pA2 values for antagonists against NAd in the thoracic aorta of WT and α1B-KO mice
| WT mice | α1B-KO mice | |||
|---|---|---|---|---|
| Antagonist | pA2 value | Slope | pA2 value | Slope |
| Prazosin | 9.99±0.15 | 1.18±0.08 | 10.41±0.04 | 0.92±0.05 |
| KMD-3213 | 8.25±0.04 | 1.06±0.04 | 8.49±0.11 | 1.09±0.06 |
| BMY7378 | 8.46±0.22 | 0.99±0.01 | 9.13±0.10 | 1.06±0.05 |
Each value represents the mean±s.e. of 5–10 experiments.