Table 2.
pA2 values for antagonists against NAd in the mesenteric artery of WT and α1B-KO mice
| WT mice | α1B-KO mice | |||
|---|---|---|---|---|
| Antagonist | pA2 value | Slope | pA2 value | Slope |
| Prazosin | 9.92±0.11 | 0.96±0.07 | 9.83±0.06 | 1.24±0.14 |
| KMD-3213 | 8.34±0.40 | 1.36±0.19 | 8.11±0.05 | 1.06±0.06 |
| BMY7378 | 7.47±0.18 | 1.08±0.12 | 7.82±0.10 | 1.02±0.11 |
Each value represents the mean±s.e. of 6–10 experiments.