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Clinical status of a C57BL/6 mouse with EAMG before and after treatment with the dual analog. (A) A representative C57BL/6 mouse after immunization and boost with Torpedo AChR α-subunit. The myasthenic decrements determined at that time by electromyography (see Materials and Methods) are shown. (B) The same mouse after 6 wk of treatment with the dual analog administered orally. No myasthenic decrement could be detected by electromyography.
