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. 2000 Feb 18;97(5):2214–2219. doi: 10.1073/pnas.040548097

Figure 8.

Figure 8

Iron status and hepatic TfR2 mRNA expression in control and HFE knockout mice. Serum transferrin saturations (A), hepatic iron concentrations (B), and relative TfR2 liver mRNA contents (C) are compared in control mice (HFE +/+, open bars) and HFE knockout mice (−/−, shaded bars) maintained on a standard diet. TfR2 mRNA levels were normalized to those for β-actin and are expressed relative to the mean of the control (+/+) group. TfR mRNA levels were not significantly different between HFE −/− and control mice. Values are expressed as mean +/− SEM (n = 5, each group). *, P < 0.05 by Student's t test, with Welch's correction for unequal variance.