Table 1.
Description of Caribbean Hispanic families
| Characteristics | First stage | Second stage |
|---|---|---|
| Number of families | 96 | 104 |
| Number of relatives examined | 394 | 417 |
| Individuals per family | 5.1 | 5.1 |
| Proportion of women (%) | 66.7% | 66.8% |
| Mean age at onset of AD (years) | 73.6 | 73.5 |
| Affection status | ||
| Probable AD | 60.2% | 60.1% |
| Unaffected | 35.3% | 36.3% |
| Unknown | 4.5% | 3.6% |
| Families with: | ||
| ≥5 affecteds | 12 (82:54) | 12 (82:55) |
| 4 affecteds | 12 (48:24) | 13 (52:27) |
| 3 affecteds | 21 (63:38) | 21 (63:42) |
| 2 affecteds | 51 (102:57) | 58 (116:65) |
| Totala | 96 (295:173) | 104 (313:189) |
| APOE—ε4 allele frequency | ||
| Probable AD | 48.8% | 47.0% |
| Unaffected | 35.8% | 35.4% |
a
In all, 22 individuals were classified as unknown.