. 2006 Apr-Jun;12(4-6):105–114. doi: 10.2119/2006-00010.Yang

Table 1.

Effect of treatment with anti-HMGB1 antibody on several parameters measured at 4 h after HS/R or the sham procedure in mice.

Parameter	Normal	Sham	IgG	aHMGB1
n	6	6	6	6
FD4 clearance (nL min⁻¹ cm⁻¹)	14 ± 1	24 ± 2^a	35 ± 6^b	29 ± 6
Bacterial translocation (CFU/g)	17 ± 17	374 ± 251^a	258 ± 216	241 ± 198
Serum IL-6 concentration (pg/mL)	0 ± 0	49 ± 8^a	360 ± 161^b	262 ± 54^b
Serum IL-10 concentration (pg/mL)	7 ± 2	19 ± 5^a	173 ± 35^b	193 ± 40^b
Serum ALT concentration (pg/mL)	40 ± 2	55 ± 4	130 ± 22^b	103 ± 20^b

P < 0.05 sham vs. normal;

P < 0.05 IgG vs. sham. None of the contrasts between the IgG and aHMGB1 groups were statistically significant.