Table 1.

Upregulated genes in 3-month-old HBV transgenic mice.

Gene Function and GenBank Acc. No.	Gene Description	Gene Symbol	Fold Change
Immunological function
M13018	Cysteine-rich protein 1 (intestinal)	Crip1	33.58
Z80112	Chemokine orphan receptor 1	Cmkor1	4.91
X52643	Histocompatibility 2, class II antigen A, alpha	H2-Aa	17.80
M21932	Histocompatibility 2, class II antigen A, beta 1	H2-Ab1	8.01
U16985	Lymphotoxin B	Ltb	8.76
X00496	Ia-associated invariant chain	Ii	7.38
J04170	CD72 antigen	Cd72	4.98
Ubiquitination
AI788534	Ring finger protein 8	Rnf8	11.65
NF-κB signal transduction cascades
M84487	Vascular cell adhesion molecule 1	Vcam1	5.06
AF000236	Chemokine (C-X-C motif) receptor 4	Cxcr4	5.04
One-carbon compound metabolism
M25944	Carbonic anhydrase 2	Car2	6.51
Regulation of transcription
X67668	High mobility group box 2	Hmgb2	5.44
AF087434	Nuclear factor of activated T-cells, cytoplasmic 1	Nfatc1	18.56
AI852641	Nuclear protein 1	Nupr1	72.44
AK217100	Activating transcription factor 3	Atf3	3.8
Intracellular calcium ion mobilization
L36860	Guanylate cyclase activator 1a (retina)	Guca1	15.14
AJ222586	Nucleobindin 2	Nucb2	9.69
AF035645	Protein tyrosine phosphatase 4a3	Ptp4a3	4.99
U20159	Lymphocyte cytosolic protein 2	Lcp2	4.43
Regulation of cell cycle and proliferation
U19597	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	Cdkn2d	3.71
AF099973	Schlafen 2	Slfn2	9.76
Actin cytoskeleton organization and biogenesis
AI852553	Thymosin, beta 10	Tmsb10	4.27
M60474	Myristoylated alanine rich protein kinase C substrate	Marcks	3.66
Protein modification
X61232	Carboxypeptidase E	Cpe	4.63
Intracellular signalling cascade
AA189555	RIKEN cDNA F630107H02 gene	F630107H02Rik	8.13