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Effect of the thrombin receptor agonist peptide on OGD-induced degeneration
| Agonist, μM | OGD, min | Cellular damage
|
|||
|---|---|---|---|---|---|
| % | SEM | n | P | ||
| Control | 30 | 100 | 0.0 | 7 | |
| 1 | 30 | 82 | 13.0 | 4 | 0.263 |
| 10 | 30 | 61* | 6.6 | 3 | 0.027 |
Hippocampal slice cultures were exposed to different agonist concentrations 30 min before and during OGD. The neuronal survival was quantified 24 h after OGD. *, P < 0.05.
