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. 1968 Oct;3(8):801–808.

Modification of the graft-versus-host syndrome by anti-lymphocyte serum treatment of the host

J L Boak, R K Dagher, J M Corson, R E Wilson
PMCID: PMC1578972  PMID: 5718504

Abstract

The effect of administering anti-lymphocyte serum (ALS) to the F1 hybrid recipient at various time intervals before and after the injection of parental donor cells has been investigated. The graft-versus-host (GVH) response can be completely inhibited by a single ALS injection given a short while before the injection of parental cells. ALS injected after the injection of donor cells fails to influence the GVH response.

It is considered that these studies confirm the view that ALS acts mainly on circulating lymphocytes and that a single ALS injection does not influence lymphocytes resident in spleen and lymph nodes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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