Table 1.
Bilirubin μmol/l ** | ASAT U/l * | Liver weight (gram) * | Spleen weight (gram)* | |
Sham | 2.7 (0.5) | 332 (143) | 9.1 (0.8) | 0.64 (0.10) |
Sham+LPS | 3.2 (0.89 | 345 (156) | 8.8 (0.8) | 0.76 (0.12) |
Cirrhosis | 39.5 (3.8) | 519 (210) | 18.5 (2.8) | 1.37 (0.42) |
Cirrhosis+LPS | 54.2 (7.8) | 912 (406) | 16.5 (2.4) | 1.27 (0.20) |
Values are given as: mean (SD). Bilirubin and ASAT (n = 9) and liver/spleen-weights (n = 10) in sham-operated, in sham-operated injected with LPS (bilirubin and ASAT: n = 10, liver/spleen-weights: n = 12), in cirrhotic (bilirubin and ASAT: n = 11, liver/spleen-weights: n = 12) and in cirrhotic animals injected with LPS (n = 9). **Significantly increased (2-way ANOVA, P < 0.001) by both factors i.e. LPS and cirrhosis. *Significantly increased only by cirrhosis (2-way ANOVA, P < 0.001).