. 2006 Aug 31;6:37. doi: 10.1186/1471-2261-6-37

Table 3.

Parameter estimates from segregation analysis of residual LV mass values: Class D regressive models, conditional on proband phenotypes

Model	Pure familial correlation, i.e. polygenic		Pure major gene (Mendel)		Mendel + familial correlation (mixed codominant)		A Dominant, μ_AB= μ_AA		A Recessive, i.e. B Dominant, μ_AB= μ_BB		Unrestricted, general

	Parameter	S.E.	Parameter	S.E.	Parameter	S.E.	Parameter	S.E.	Parameter	S.E.	Parameter	S.E.
qA	[1]		0.098	0.028	0.093	0.030	0.040	0.020	0.000	0.142	0.109	0.024
τ_AA	-		[1]		[1]		[1]		[1]		1.000	0.000
τ_AB	-		[0.5]		[0.5]		[1]		[1]		0.249	0.100
τ_BB	-		[0]		[0]		[0]		[0]		0.034	0.030
μ_AA	36.0	0.5	64.4	4.3	65.1	4.5	51.4	2.8	40.9	8.2	62.7	3.4
μ_AB	= μ_AA		45.6	1.8	45.7	1.9	51.4	2.8	36.0	0.5	46.1	1.4
μ_BB	= μ_AA		33.7	0.5	33.9	0.6	34.9	0.6	36.0	0.5	33.5	0.6
σ²	80.6	4.6	52.4	4.2	53.5	4.7	61.8	5.5	80.6	4.6	47.1	4.9
ρ_MF	0.199	0.072	0.327	0.093	0.315	0.091	0.246	0.079	0.199	0.072	0.334	0.098
ρ_MO	0.196	0.050	[0]		0.058	0.070	0.130	0.067	0.196	0.050	0.076	0.079
ρ_FO	0.093	0.059	[0]		-0.070	0.069	-0.025	0.064	0.093	0.059	-0.051	0.076
ρ_SS	0.118	0.055	[0]		0.000	0.000	0.037	0.069	0.118	0.055	0.017	0.065
# of	6		6		9		8		8		12
parameters
-2ln(L)	4721.80		4684.40		4682.38		4688.22		4721.80		4677.90
AIC	4733.8		4696.4		4700.38		4704.22		4737.8		4701.9
χ²	43.9		6.5		4.48		10.32		43.9
P	0.000		0.370		0.214		0.035		0.000		Baseline

Abbreviation: qA, allele frequency; τ_AA, τ_AB, τ_BB, transmission probability; μ_AA, μ_AB, μ_BB, genotype means; σ², variance; ρ_MF, ρ_MO, ρ_FO, ρ_SS, correlation coefficients among spouse, mother-offspring, father-ffspring and sibling pairs; #, number of parameters; ln(L), logarithm of likelihood; AIC, Akaike information criteria; P, p-value by compared with the unrestricted general model.