Table 2.
% of TrkB (+) neurons | % of TrkC (+) neurons | |
---|---|---|
wt | 11.3 ± 0.3% | 7.8 ± 0.8% |
NT-4 −/− | 1.2 ± 0.4% | 16.8 ± 0.5% |
P value | P < 0.0001 | P < 0.0001 |
Percentage of TrkB- and TrkC-expressing neurons of the lumbar DRG were counted in sections of the midganglia in wt and NT-4 mutant mice. The number of Trk-positive neurons (Fig. 3 a–j) was compared with total neuron counts (≈2,000–4,000 neurons) in the same lumbar sections (10 sections per animal). Student's t test determined the significance levels. n = 4.